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CD147 Antibody

This antibody recognizes extracellular epitope 2 within the N-terminal Ig domain of human CD147. It expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. CD147 stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes are important factors in cancer invasion and metastasis.

Product Specifications

CAS Number

9007-83-4

Specifications

The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Host

Mouse

Reactivity

Human

Immunogen

Human T cell line Molt-13 was used as the immunogen for this CD147 antibody.

Clonality

Monoclonal

Isotype

IgG1 k

Clone

8D6

Applications

IHC-P

Purity

Protein G purified CD147 antibody

Format

Purified

Buffer

1X PBS, pH 7.4

Reconstitution

Store the CD147 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This CD147 antibody is available for research use only.

Storage Conditions

Store the CD147 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Product Datasheet

https://www.nsjbio.com/tds-pdf/cd147-antibody-8d6-v2015

Formulation

Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05% sodium azide; *For IHC use only*

Location

Cell surface, cytoplasmic

Image Legend

IHC testing of FFPE human renal cell carcinoma with CD147 antibody (clone 8D6) .

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