PERM (light chain, Cleaved-Gly278) rabbit pAb

Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils. [provided by RefSeq, Nov 2014],

Product Specifications

Background

UniProt

P05164

Swiss Prot

P05164

Reactivity

Human; Rat; Mouse

Immunogen

Synthesized peptide derived from human PERM (light chain, Cleaved-Gly278)

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC

Concentration

1 mg/ml

Dilution

WB 1:500-2000; IHC-p 1:50-300

Molecular Weight

12 84 89kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

12 84 89kD

Fragment

IgG

Subcellular Location

Lysosome.

Other Product Names

Myeloperoxidase (MPO; EC 1.11.2.2) [Cleaved into: Myeloperoxidase; 89 kDa myeloperoxidase; 84 kDa myeloperoxidase; Myeloperoxidase light chain; Myeloperoxidase heavy chain]