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Sentrin-specific protease 1 Antibody / SENP1

Sentrin-specific protease 1 is a protein that in human is encoded by the SENP1 gene. This gene is mapped to 12q13.11. This gene encodes a cysteine protease that specifically targets members of the small ubiquitin-like modifier (SUMO) protein family. This protease regulates SUMO pathways by deconjugating sumoylated proteins. This protease also functions to process the precursor SUMO proteins into their mature form. Alternate splicing results in multiple transcript variants.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1-2 µg/mL, Flow cytometry: 1-3ug/million cells

UniProt

Q9P0U3

Host

Mouse

Reactivity

Human

Immunogen

Recombinant human protein (amino acids N19-P619) was used as the immunogen for the Sentrin-specific protease 1 antibody.

Clonality

Monoclonal

Isotype

IgG1

Clone

5F4

Applications

WB, FACS

Purity

Affinity purified

Format

Purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose

Reconstitution

After reconstitution, the Sentrin-specific protease 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This Sentrin-specific protease 1 antibody is available for research use only.

Storage Conditions

After reconstitution, the Sentrin-specific protease 1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the Sentrin-specific protease 1 antibody should be determined by the researcher.

Image Legend

Flow cytometry testing of human K562 cells with Sentrin-specific protease 1 antibody at 1ug/million cells (blocked with goat sera) ; Red=cells alone, Green=isotype control, Blue= Sentrin-specific protease 1 antibody.

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