UBAP2L Antibody / Ubiquitin-associated protein 2-like

Ubiquitin-associated protein 2-like is a protein that in humans is encoded by the UBAP2L gene. Ubiquitin-associated protein 2-like (UBAP2L), which contains a ubiquitin-associated (UBA) domain near its N-terminus, has been indicated in the pathogenesis of several human cancers, including multiple myeloma, hepatocellular carcinoma, and malignant ovarian tumors. UBAP2L is closely associated with tumor growth and metastasis. UBAP2L has a key role in glioma cell growth and may act as an oncogene to promote malignant glioma development. UBAP2L also plays an important role in breast cancer cell proliferation and might serve as a potential target for breast cancer treatment. UBAP2L plays a critical role in the maintenance of the metastatic ability of hepatocellular carcinoma (HCC) cells via SNAIL1 Regulation and is predictive of a poor clinical outcome.