SOX7 Antibody
SOX7 belongs to SOX gene family and SOX proteins are transcription factors with critical roles in the regulation of diverse developmental processes. This gene is mapped to 8p23.1. SOX7 gene contains at least 2 exons. In co-transfected 293 cells, Sox7 reduced Wnt/beta-catenin-stimulated transcription. SOX7 is a potent activator of FGF3 transcription. It not only plays a role in the transcriptional regulation of genes expressed in the hemogenic endothelium but also blocks further differentiation into blood precursors. And it may be required for the survival of both hematopoietic and endothelial precursors during specification.
Product Specifications
Specifications
Western blot: 1-2 µg/mL, Direct ELISA: 0.1-0.5 µg/mL
UniProt
Q9BT81
Host
Rabbit
Reactivity
Human
Immunogen
An E. coli-derived human protein (amino acids K57-D343) was used as the immunogen for the SOX7 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, Direct ELISA
Purity
Affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
Limitations
This SOX7 antibody is available for research use only.
Storage Conditions
Product Datasheet
https://www.nsjbio.com/tds-pdf/sox7-antibody-rq6519
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the SOX7 antibody should be determined by the researcher.
CAS Number
9007-83-4
Image Legend
Western blot testing of human 1) COLO-320, 2) PC-3 and 3) A431 cell lysate with SOX7 antibody. Predicted molecular weight: 42/49 kDa (isoforms 1/2) .
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