HFH-4 Antibody / FOXJ1

Forkhead box protein J1, also called Hepatocyte nuclear factor 3 forkhead homolog 4 or HFH-4, is a protein that in humans is encoded by the FOXJ1 gene. This gene encodes a member of the forkhead family of transcription factors. Similar genes in zebrafish and mouse have been shown to regulate the transcription of genes that control the production of motile cilia. The mouse ortholog also functions in the determination of left-right asymmetry. Polymorphisms in this gene are associated with systemic lupus erythematosus and allergic rhinitis.