SAMHD1 Antibody
SAM domain and HD domain-containing protein 1 is a protein that in humans is encoded by the SAMHD1 gene. This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL, Immunofluorescence (FFPE) : 5 µg/mL, Flow cytometry: 1-3ug/million cells
UniProt
Q9Y3Z3
Host
Mouse
Reactivity
Human
Immunogen
Recombinant human protein (amino acids E37-M626) was used as the immunogen for the SAMHD1 antibody.
Clonality
Monoclonal
Isotype
IgG1
Clone
3B9
Applications
WB, IHC-P, IF, FACS
Purity
Antigen affinity purified
Format
Purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
Limitations
This SAMHD1 antibody is available for research use only.
Storage Conditions
Product Datasheet
https://www.nsjbio.com/tds-pdf/samhd1-antibody-3b9-rq6377
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the SAMHD1 antibody should be determined by the researcher.
Location
Nuclear
Image Legend
IHC staining of FFPE human lymphoma tissue with SAMHD1 antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.
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