CASP7 Antibody / Caspase-7
Caspase-7 is a human protein encoded by the CASP7 gene. CASP7 orthologs have been identified in nearly all mammals for which complete genome data are available. CASP7 is a member of the caspase (cysteine aspartate protease) family of proteins, and has been shown to be an executioner protein of apoptosis. Using radiation hybrid mapping, the CASP7 gene was localized to human chromosome 10q25.1-q25.2. The orderly activation of CASP7 regulates microglia activation through a protein kinase C-delta (PRKCD) -dependent pathway.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL, Direct ELISA: 0.1-0.5 µg/mL
UniProt
P55210
Host
Rabbit
Reactivity
Human, Rat
Immunogen
Recombinant human protein (amino acids A24-Q303) was used as the immunogen for the CASP7 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, Direct ELISA
Purity
Antigen affinity purified
Format
Purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
Limitations
This CASP7 antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the CASP7 antibody should be determined by the researcher.
Location
Cytoplasmic
Image Legend
IHC staining of FFPE human rectal cancer with CASP7 antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items