UBR2 Antibody
E3 ubiquitin-protein ligase UBR2 is an enzyme that in humans is encoded by the UBR2 gene. It is mapped to 6p21.1. This gene encodes an E3 ubiquitin ligase of the N-end rule proteolytic pathway that targets proteins with destabilizing N-terminal residues for polyubiquitylation and proteasome-mediated degradation. Alternative splicing results in multiple transcript variants.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1-2 µg/mL
UniProt
Q8IWV8
Host
Mouse
Reactivity
Human
Immunogen
A human recombinant partial protein (amino acids Q10-A664) was used as the immunogen for the UBR2 antibody.
Clonality
Monoclonal
Isotype
IgG2a
Clone
2G11
Applications
WB
Purity
Affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
Limitations
This UBR2 antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the UBR2 antibody should be determined by the researcher.
Image Legend
Western blot testing of human 1) HEK293, 2) Jurkat and 3) K562 cell lysate with UBR2 antibody. Predicted molecular weight ~202 kDa.
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items