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UBR2 Antibody

E3 ubiquitin-protein ligase UBR2 is an enzyme that in humans is encoded by the UBR2 gene. It is mapped to 6p21.1. This gene encodes an E3 ubiquitin ligase of the N-end rule proteolytic pathway that targets proteins with destabilizing N-terminal residues for polyubiquitylation and proteasome-mediated degradation. Alternative splicing results in multiple transcript variants.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1-2 µg/mL

UniProt

Q8IWV8

Host

Mouse

Reactivity

Human

Immunogen

A human recombinant partial protein (amino acids Q10-A664) was used as the immunogen for the UBR2 antibody.

Clonality

Monoclonal

Isotype

IgG2a

Clone

2G11

Applications

WB

Purity

Affinity purified

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose

Reconstitution

After reconstitution, the UBR2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This UBR2 antibody is available for research use only.

Storage Conditions

After reconstitution, the UBR2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the UBR2 antibody should be determined by the researcher.

Image Legend

Western blot testing of human 1) HEK293, 2) Jurkat and 3) K562 cell lysate with UBR2 antibody. Predicted molecular weight ~202 kDa.

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