(+) -U-50488
(+) -U-50488 ((+) -Trans- (1R,2R) -U-50488) is a less active κ opioid receptor (KOR) agonist than the enantiomer of (-) -Trans- (1S,2S) -U-50488.
Product Specifications
CAS Number
67198-17-8
Product Name Alternative
(+) -Trans- (1R,2R) -U-50488
UNSPSC
12352005
Target
Opioid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/plus-u-50488.html
Solubility
10 mM in DMSO
Smiles
O=C(N(C)[C@H]1[C@H](N2CCCC2)CCCC1)CC3=CC=C(Cl)C(Cl)=C3
Molecular Formula
C19H26Cl2N2O
Molecular Weight
369.33
References & Citations
[1]DeCosta B, et al. Synthesis and absolute configuration of optically pure enantiomers of a kappa-opioid receptor selective agonist. FEBS Lett. 1987;223 (2) :335-339.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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