PARP9 Antibody
Poly (ADP-ribosyl) ation is a post-translational modification of proteins mediated by one of the 17 members of the poly (ADP-ribose) polymerases (PARP) . PARP-9 belongs to the subfamily of macroPARPs, associating one to three macro domains to the PARP domain. Overexpression of PARP-9 stimulates cell migration in vitro, suggesting a role for PARP-9 in the promotion of malignant B cell migration and dissemination in high risk DLBCL. PARP-9 is also likely a transcription coactivator, its overexpression in B lymphocytes, stimulated by IFN?, inducing the transcription of IFN?-controlled genes.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1-2 µg/mL, Direct ELISA: 0.1-0.5 µg/mL
UniProt
Q8IXQ6
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A human recombinant partial protein (amino acids R117-E824) was used as the immunogen for the PARP9 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, Direct ELISA
Purity
Affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
Limitations
This PARP9 antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the PARP9 antibody should be determined by the researcher.
Image Legend
Western blot testing of 1) rat skeletal muscle and 2) mouse skeletal muscle lysate with PARP9 antibody. Predicted molecular weight ~96 kDa.
Documents
Frequently Asked Questions
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