ASS1 Antibody / Argininosuccinate synthetase 1
Argininosuccinate synthetase is an enzyme that in humans is encoded by the ASS1 gene. It is mapped to 9q34.11. The protein encoded by this gene catalyzes the penultimate step of the arginine biosynthetic pathway. There are approximately 10 to 14 copies of this gene including the pseudogenes scattered across the human genome, among which the one located on chromosome 9 appears to be the only functional gene for argininosuccinate synthetase. Mutations in the chromosome 9 copy of this gene cause citrullinemia. Two transcript variants encoding the same protein have been found for this gene.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1-2 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL, Immunofluorescence: 5 µg/mL, Flow cytometry: 1-3ug/million cells
UniProt
P00966
Host
Mouse
Reactivity
Human, Mouse, Rat, Monkey
Immunogen
A human recombinant partial protein (amino acids S3-S365) was used as the immunogen for the ASS1 antibody.
Clonality
Monoclonal
Isotype
IgG2b
Clone
7I9
Applications
WB, IHC-P, IF, FACS
Purity
Affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
Limitations
This ASS1 antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the ASS1 antibody should be determined by the researcher.
Image Legend
IHC staining of FFPE human breast cancer with ASS1 antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.
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