METTL1 Antibody
TRNA (guanine-N (7) -) -methyltransferase is an enzyme that in humans is encoded by the METTL1 gene. This gene is similar in sequence to the S. cerevisiae YDL201w gene. The gene product contains a conserved S-adenosylmethionine-binding motif and is inactivated by phosphorylation. Alternative splice variants encoding different protein isoforms have been described for this gene. A pseudogene has been identified on chromosome X.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1-2 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL, Immunofluorescence: 5 µg/mL, Direct ELISA: 0.1-0.5 µg/mL
UniProt
Q9UBP6
Host
Rabbit
Reactivity
Human, Rat
Immunogen
A human recombinant partial protein (amino acids A2-H276) was used as the immunogen for the METTL1 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, IF, Direct ELISA
Purity
Affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
Limitations
This METTL1 antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the METTL1 antibody should be determined by the researcher.
Location
Nuclear
Image Legend
IHC staining of FFPE human breast cancer with METTL1 antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.
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