IL-23 Receptor Antibody

Interleukin 23 receptor is a type I cytokine receptor. IL23R is its human gene. The protein encoded by this gene is a subunit of the receptor for IL23A/IL23. This protein pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. This protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1-2 µg/mL, Flow cytometry: 1-3ug/million cells, Direct ELISA: 0.1-0.5 µg/mL

UniProt

Q5VWK5

Host

Rabbit

Reactivity

Human

Immunogen

A human recombinant partial protein (amino acids Q76-Q 305) was used as the immunogen for the IL-23 Receptor antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB, FACS, Direct ELISA

Purity

Affinity purified

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose and 0.0125% sodium azide

Reconstitution

After reconstitution, the IL-23 Receptor antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This IL-23 Receptor antibody is available for research use only.

Storage Conditions

After reconstitution, the IL-23 Receptor antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the IL-23 Receptor antibody should be determined by the researcher.

Image Legend

Flow cytometry testing of human PBM cells with IL-23 Receptor antibody at 1ug/million cells (blocked with goat sera) ; Red=cells alone, Green=isotype control, Blue= IL-23 Receptor antibody.