IKKI Antibody / IKKE / IKBKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon also known as I-kappa-B kinase epsilon or IKK-epsilon is an enzyme that in humans is encoded by the IKBKE gene. IKBKE is a noncanonical I-kappa-B kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell line.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1-2 µg/mL, Direct ELISA: 0.1-0.5 µg/mL
UniProt
Q14164
Host
Rabbit
Reactivity
Human
Immunogen
A human recombinant partial protein (amino acids Q318-V716) was used as the immunogen for the IKKI antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, Direct ELISA
Purity
Affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
Limitations
This IKKI antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the IKKI antibody should be determined by the researcher.
Image Legend
Western blot testing of human 1) HL60, 2) U-87 MG and 3) A549 cell lysate with IKKI antibody. Predicted molecular weight: 71-80 kDa.
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