PECAM-1 Antibody / CD31
CD31 also known as Platelet endothelial cell adhesion molecule (PECAM-1), is a protein that in human is encoded by the PECAM1 gene. Encoded protein is a member of the immunoglobulin superfamily and this gene is mapped to 17q23.3. CD31 is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. It is demonstrated that CD31 expression on human PBSCs may positively affect both neutrophil and platelet engraftment. Meanwhile, CD31 is involved in leukocyte migration and angiogenesis, which are key components of venous thrombus resolution.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Immunohistochemistry: 1-2 µg/mL, Direct ELISA: 0.1-0.5 µg/mL
UniProt
Q3SWT0
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant rat protein (amino acids Q41-E491) was used as the immunogen for the PECAM-1 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, Direct ELISA
Purity
Affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
Limitations
This PECAM-1 antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the PECAM-1 antibody should be determined by the researcher.
Image Legend
IHC staining of FFPE human placenta with PECAM-1 antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.
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