Octenidine
Octenidine is a potent antibacterial agent, possessing activity against multidrug-resistant Gram-negative pathogens. Octenidine can inhibit the expression of biofilm genes and destroy the formation of biofilms[1][3].
Product Specifications
CAS Number
71251-02-0
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/octenidine.html
Solubility
10 mM in DMSO
Smiles
CCCCCCCC/N=C1C=CN(CCCCCCCCCCN(C=C/2)C=CC2=N/CCCCCCCC)C=C/1
Molecular Formula
C36H62N4
Molecular Weight
550.90
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Alvarez-Marin R, et al. Antimicrobial activity of octenidine against multidrug-resistant Gram-negative pathogens. Eur J Clin Microbiol Infect Dis. 2017 Dec;36 (12) :2379-2383.|[2]Conceição T, et al. Efficacy of octenidine against antibiotic-resistant Staphylococcus aureus epidemic clones. J Antimicrob Chemother. 2016 Oct;71 (10) :2991-4.|[3]Huang J, et al. Octenidine dihydrochloride treatment of a meticillin-resistant Staphylococcus aureus biofilm-infected mouse wound. J Wound Care. 2021 Feb 2;30 (2) :106-114.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 4
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