SMAD5 Antibody
Mothers against decapentaplegic homolog 5 also known as SMAD5 is a protein that in humans is encoded by the SMAD5 gene. It is mapped to 5q31.1. The protein encoded by this gene is involved in the transforming growth factor beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. The encoded protein is activated by bone morphogenetic proteins type 1 receptor kinase, and may be involved in cancer. Alternative splicing results in multiple transcript variants.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
UniProt
Q99717
Host
Rabbit
Reactivity
Human, Mouse, Rat, Monkey
Immunogen
Amino acids QNATFPDSFHQPNNTPFPLSPN from the human protein were used as the immunogen for the SMAD5 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
Limitations
This SMAD5 antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the SMAD5 antibody should be determined by the researcher.
Location
Nuclear, cytoplasmic
Image Legend
Western blot testing of 1) rat liver and 2) mouse liver lysate with SMAD5 antibody. Expected molecular weight: 52~60 kDa.
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