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Beta NGF Antibody / NGF

Nerve growth factor (NGF) is a neurotrophic factor and neuropeptide primarily involved in the regulation of growth, maintenance, proliferation, and survival of certain target neurons. It is mapped to 1p13.2. This gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this gene's expression is associated with allergic rhinitis.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.5-1 µg/mL

UniProt

P01138

Host

Rabbit

Reactivity

Human

Immunogen

Amino acids THTFVKALTMDGKQAAWRFIRID from the human protein were used as the immunogen for the Beta NGF antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB

Purity

Affinity purified

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide

Reconstitution

After reconstitution, the Beta NGF antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This Beta NGF antibody is available for research use only.

Storage Conditions

After reconstitution, the Beta NGF antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the NGF antibody should be determined by the researcher.

Image Legend

Western blot testing of human 1) U-87 MG, 2) 22RV1 and 3) A549 lysate with Beta NGF antibody. Predicted molecular weight ~27 kDa (dimer) .

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