Gasdermin D Antibody / GSDMD

Gasdermin D is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. Gasdermin D has been suggested to act as a tumor suppressor. Alternatively spliced transcript variants have been described.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.5-1 µg/mL, Immunohistochemistry: 1-2 µg/mL, Flow cytometry: 1-3ug/million cells, Direct ELISA: 0.1-0.5 µg/mL

UniProt

P57764

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant human protein (amino acids M1-H484) was used as the immunogen for the Gasdermin D antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB, IHC-P, FACS, Direct ELISA

Purity

Affinity purified

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide

Reconstitution

After reconstitution, the Gasdermin D antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This Gasdermin D antibody is available for research use only.

Storage Conditions

After reconstitution, the Gasdermin D antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the Gasdermin D antibody should be determined by the researcher.

Image Legend

IHC staining of FFPE human rectal cancer with Gasdermin D antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.