B-ARK1 Antibody / GRK2
Beta adrenergic receptor kinase (beta-ARK or BARK) is a serine/threonine intracellular kinase. The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Flow cytometry: 1-3ug/million cells, Immunofluorescence: 2-4 µg/mL
UniProt
P25098
Host
Rabbit
Reactivity
Human, Mouse, Rat, Monkey
Immunogen
Amino acids KKELRDAYREAQQLVQRV from the human protein were used as the immunogen for the B-ARK1 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, FACS, IF
Purity
Affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
Limitations
This B-ARK1 antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the B-ARK1 antibody should be determined by the researcher.
Image Legend
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
![VEGFD Rabbit Monoclonal Antibody [Clone ID: 24GB1750]](https://cdn.genprice.uk/genprice/uk/genprice5.webp)
VEGFD Rabbit Monoclonal Antibody [Clone ID: 24GB1750]
Potassium Phosphate Dibasic Anhydrous 99% Molecular Biology
Recombinant Human ADCK1 Protein - (Dry Ice)
4,4'- (1,3,8,10-Tetraoxo-1,3,8,10-tetrahydroanthra[2,1,9-def:6,5,10-d'e'f']diisoquinoline-2,9-diyl) dibenzoic acid