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BAG-1 Antibody

BAG family molecular chaperone regulator 1 (BAG1) is a protein that in humans is encoded by the BAG1 gene. Human BAG1 is mapped to chromosome 9p12, a region associated with hereditary disorders that may involve developmental dysregulation of programmed cell death. The Bag1 protein is rich in glutamic acid residues. Its deduced 274-amino acid protein has a calculated molecular mass of 31 KD. Being the BCL-2-associated athanogene, Bag1 enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.5-1 µg/mL

UniProt

Q99933

Host

Rabbit

Reactivity

Human

Immunogen

Amino acids LVKKVQAFLAECDTVEQNICQETERLQSTNFALAE from the human protein were used as the immunogen for the BAG-1 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB

Purity

Affinity purified

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose

Reconstitution

After reconstitution, the BAG-1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This BAG-1 antibody is available for research use only.

Storage Conditions

After reconstitution, the BAG-1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the BAG-1 antibody should be determined by the researcher.

Image Legend

Western blot testing of human 1) HepG2 and 2) A549 cell lysate with BAG-1 antibody. Predicted molecular weight ~50 kDa (long form), 29-33 (short form) .

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