USP16 Antibody
Ubiquitin carboxyl-terminal hydrolase 16 is an enzyme that in humans is encoded by the USP16 gene. It is mapped to 21q21.3. This gene encodes a deubiquitinating enzyme that is phosphorylated at the onset of mitosis and then dephosphorylated at the metaphase/anaphase transition. It can deubiquitinate H2A, one of two major ubiquitinated proteins of chromatin, in vitro and a mutant form of the protein was shown to block cell division. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Product Specifications
CAS Number
9007-83-4
Specifications
UniProt
Q9Y5T5
Host
Rabbit
Reactivity
Human, Rat, Monkey
Immunogen
Recombinant human protein (amino acids K9-L823) was used as the immunogen for the USP16 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, IF, FACS, Direct ELISA
Purity
Affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
Limitations
This USP16 antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the USP16 antibody should be determined by the researcher.
Image Legend
IHC staining of FFPE human lung cancer with USP16 antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.
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