Niemann Pick C2 Antibody / NPC2
Epididymal secretory protein E1 (also called NPC intracellular cholesterol transporter 2, or NPC2) is a protein associated with Niemann-Pick disease, type C. It is mapped to 14q24.3. This gene encodes a protein containing a lipid recognition domain. The encoded protein may function in regulating the transport of cholesterol through the late endosomal/lysosomal system. Mutations in this gene have been associated with Niemann-Pick disease, type C2 and frontal lobe atrophy.
Product Specifications
CAS Number
9007-83-4
Specifications
UniProt
P61916
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant human protein (amino acids E20-L151) was used as the immunogen for the Niemann Pick C2 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, IF, FACS, Direct ELISA
Purity
Affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
Limitations
This Niemann Pick C2 antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the Niemann Pick C2 antibody should be determined by the researcher.
Image Legend
IHC staining of FFPE human tonsil with Niemann Pick C2 antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.
Documents
Frequently Asked Questions
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