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Tafazzin Antibody

Tafazzin, also known as G4.5 is a protein that in humans is encoded by the TAZ gene. Cardiolipin is a complex glycerophospholipid with 4 acyl groups that localizes to the mitochondrial inner membrane and has a role in mitochondrial structure and function. By positional cloning, TAZ was identified within the critical Barth syndrome region on Xq28. Tafazzin is involved in the metabolism of cardiolipin. It is a component of the hippo signaling pathway that controls tissue growth in animals. And it can function as aphospholipid lysophospholipid transacylase.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL, Direct ELISA: 0.1-0.5 µg/mL

UniProt

Q16635

Host

Rabbit

Reactivity

Human

Immunogen

A human recombinant protein (amino acids M73-R292) was used as the immunogen for the Tafazzin antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB, IHC-P, Direct ELISA

Purity

Affinity purified

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide

Reconstitution

After reconstitution, the Tafazzin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This Tafazzin antibody is available for research use only.

Storage Conditions

After reconstitution, the Tafazzin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the Tafazzin antibody should be determined by the researcher.

Location

Cytoplasmic, membrane

Image Legend

IHC staining of FFPE human colon cancer with Tafazzin antibody. HIER: boil tissue sections in pH8 EDTA buffer for 20 min and allow to cool before testing.

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