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AVPR1A Antibody

Arginine vasopressin receptor 1A (officially called AVPR1A) is one of the three major receptor types forarginine vasopressin (AVPR1BandAVPR2being the others) . It belongs to the subfamily of G-protein coupled receptors which includes AVPR1B, V2R and OXT receptors. This gene is mapped to 12q14.2. AVPR1A is present throughout the brain, as well as in the periphery, in the liver, kidney, and vasculature. The protein encoded by this gene acts as receptor for arginine vasopressin. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor mediates cell contraction and proliferation, platelet aggregation, release of coagulation factor and glycogenolysis.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.25-0.5 µg/mL, Direct ELISA: 0.1-0.5 µg/mL

UniProt

P37288

Host

Rabbit

Reactivity

Human

Immunogen

A human recombinant protein (amino acids R43-K268) was used as the immunogen for the AVPR1A antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB, Direct ELISA

Purity

Affinity purified

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide

Reconstitution

After reconstitution, the AVPR1A antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This AVPR1A antibody is available for research use only.

Storage Conditions

After reconstitution, the AVPR1A antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the AVPR1A antibody should be determined by the researcher.

Image Legend

Western blot testing of human 1) A549, 2) A431, 3) HEK293, 4) ThP-1 and 5) Caco-2 cell lysate with AVPR1A antibody. Expected molecular weight: 47-85 kDa depending on glycosylation level.

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