ASIC1 Antibody
Acid-sensing ion channel 1 (ASIC1) also known as amiloride-sensitive cation channel 2, neuronal (ACCN2) or brain sodium channel 2 (BNaC2) is a protein that in humans is encoded by the ASIC1 gene. It is mapped to 12q13.12. This gene encodes a member of the acid-sensing ion channel (ASIC) family of proteins, which are part of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. Members of the ASIC family are sensitive to amiloride and function in neurotransmission. The encoded proteins function in learning, pain transduction, touch sensation, and development of memory and fear. Alternatively spliced transcript variants have been described.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 0.25-0.5 µg/mL, Direct ELISA: 0.1-0.5 µg/mL
UniProt
P78348
Host
Rabbit
Reactivity
Human
Immunogen
A human recombinant protein (amino acids H163-C528) was used as the immunogen for the ASIC1 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, Direct ELISA
Purity
Affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
Limitations
This ASIC1 antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the ASIC1 antibody should be determined by the researcher.
Image Legend
Western blot testing of human ThP-1 cell lysate with ASIC1 antibody. Predicted molecular weight ~60 kDa.
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