NME1 Antibody / NM23A
This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. [RefSeq]
Product Specifications
CAS Number
9000-83-3
Specifications
Western blot: 1:500-1:2000
UniProt
P15531
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide specific to human NM23A / NME1 was used as the immunogen for the NME1 antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
AEID-14
Type
Recombinant
Applications
WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the NME1 antibody at -20oC.
Limitations
This NME1 antibody is available for research use only.
Storage Conditions
Store the NME1 antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the NME1 antibody should be determined by the researcher.
Image Legend
Western blot testing of human Jurkat cell lysate with NME1 antibody. Predicted molecular weight ~17 kDa.
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