CREB1 Antibody

The CREB1 gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in several transcript variants encoding different isoforms. [RefSeq]

Product Specifications

CAS Number

9000-83-3

Specifications

Western blot: 1:500-1:2000, Immunohistochemistry (FFPE) : 1:50-1:200, Immunofluorescence/Immunocytochemistry: 1:50-1:200

UniProt

P16220

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A synthetic peptide specific to human CREB was used as the immunogen for the CREB1 antibody.

Clonality

Monoclonal

Isotype

IgG

Clone

DCO-3

Type

Recombinant

Applications

IF/ICC, IHC-P, WB

Purity

Affinity purified

Format

Purified

Buffer

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA

Reconstitution

Store the CREB1 antibody at -20oC.

Limitations

This CREB1 antibody is available for research use only.

Storage Conditions

Store the CREB1 antibody at -20°C.

Formulation

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA

Applications Notes

Optimal dilution of the CREB1 antibody should be determined by the researcher.

Location

Nuclear

Image Legend

IHC staining of FFPE mouse brain with CREB1 antibody. HIER: boil tissue sections in pH6, 10mM citrate buffer, for 10-20 min and allow to cool before testing.