CD104 Antibody / Integrin beta 4 / ITGB4
Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. The ITGB4 gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. [RefSeq]
Product Specifications
CAS Number
9000-83-3
Specifications
Western blot: 1:500-1:2000
UniProt
P16144
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A synthetic peptide specific to human Integrin beta 4 / ITGB4 was used as the immunogen for the CD104 antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
AAFE-9
Type
Recombinant
Applications
WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the CD104 antibody at -20oC.
Limitations
This CD104 antibody is available for research use only.
Storage Conditions
Store the CD104 antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the CD104 antibody should be determined by the researcher.
Image Legend
Western blot testing of 1) human SW480 and 2) mouse spleen lysate with CD104 antibody. Predicted molecular weight ~200 kDa.
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