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SELP Antibody / CD62P / P-Selectin

The SELP gene encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. [RefSeq]

Product Specifications

CAS Number

9000-83-3

Specifications

Western blot: 1:500-1:2000

UniProt

P16109

Host

Rabbit

Reactivity

Human

Immunogen

A synthetic peptide specific to human CD62P / SELP was used as the immunogen for the SELP antibody.

Clonality

Monoclonal

Isotype

IgG

Clone

AAEC-19

Type

Recombinant

Applications

WB

Purity

Affinity purified

Format

Purified

Buffer

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA

Reconstitution

Store the SELP antibody at -20oC.

Limitations

This SELP antibody is available for research use only.

Storage Conditions

Store the SELP antibody at -20°C.

Formulation

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA

Applications Notes

Optimal dilution of the SELP antibody should be determined by the researcher.

Image Legend

Western blot testing of HUVEC lysate with SELP antibody. Expected molecular weight: 86-140 kDa depending on glycosylation level.

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