SELP Antibody / CD62P / P-Selectin
The SELP gene encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. [RefSeq]
Product Specifications
CAS Number
9000-83-3
Specifications
Western blot: 1:500-1:2000
UniProt
P16109
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide specific to human CD62P / SELP was used as the immunogen for the SELP antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
AAEC-19
Type
Recombinant
Applications
WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the SELP antibody at -20oC.
Limitations
This SELP antibody is available for research use only.
Storage Conditions
Store the SELP antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the SELP antibody should be determined by the researcher.
Image Legend
Western blot testing of HUVEC lysate with SELP antibody. Expected molecular weight: 86-140 kDa depending on glycosylation level.
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