MMP9 Antibody / Matrix metalloproteinase-9
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling. [RefSeq]
Product Specifications
CAS Number
9000-83-3
Specifications
Western blot: 1:500-1:2000, Immunohistochemistry (FFPE) : 1:50-1:200
UniProt
P14780
Host
Rabbit
Reactivity
Human, Rat
Immunogen
A synthetic peptide specific to human MMP9 was used as the immunogen for the MMP9 antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
BCD-13
Type
Recombinant
Applications
IHC-P, WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the MMP9 antibody at -20oC.
Limitations
This MMP9 antibody is available for research use only.
Storage Conditions
Store the MMP9 antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the MMP9 antibody should be determined by the researcher.
Location
Cytoplasmic, nuclear, secreted
Image Legend
Western blot testing with MMP9 antibody. Expected molecular weight: ~92 kDa (precursor), 67-80 kDa (mature) .
Frequently Asked Questions
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