Tyrosinase Antibody / TYR
The enzyme encoded by the TYR gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. [RefSeq]
Product Specifications
CAS Number
9000-83-3
Specifications
Western blot: 1:500-1:2000
UniProt
P14679
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide specific to human Tyrosinase / TYR was used as the immunogen for the Tyrosinase antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
AAHE-20
Type
Recombinant
Applications
WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the Tyrosinase antibody at -20oC.
Limitations
This Tyrosinase antibody is available for research use only.
Storage Conditions
Store the Tyrosinase antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the Tyrosinase antibody should be determined by the researcher.
Image Legend
Western blot testing of human melanoma lysate with Tyrosinase antibody. Predicted molecular weight: 60-84 kDa depending on level of glycosylation.
Frequently Asked Questions
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