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Tyrosinase Antibody / TYR

The enzyme encoded by the TYR gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. [RefSeq]

Product Specifications

CAS Number

9000-83-3

Specifications

Western blot: 1:500-1:2000

UniProt

P14679

Host

Rabbit

Reactivity

Human

Immunogen

A synthetic peptide specific to human Tyrosinase / TYR was used as the immunogen for the Tyrosinase antibody.

Clonality

Monoclonal

Isotype

IgG

Clone

AAHE-20

Type

Recombinant

Applications

WB

Purity

Affinity purified

Format

Purified

Buffer

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA

Reconstitution

Store the Tyrosinase antibody at -20oC.

Limitations

This Tyrosinase antibody is available for research use only.

Storage Conditions

Store the Tyrosinase antibody at -20°C.

Formulation

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA

Applications Notes

Optimal dilution of the Tyrosinase antibody should be determined by the researcher.

Image Legend

Western blot testing of human melanoma lysate with Tyrosinase antibody. Predicted molecular weight: 60-84 kDa depending on level of glycosylation.

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