COX IV Antibody / COX4I1
Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. [RefSeq]
Product Specifications
CAS Number
9000-83-3
Specifications
Western blot: 1:1000-1:2000
UniProt
P13073
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide specific to human COX IV / COX4I1 was used as the immunogen for the COX IV antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
AIC-3
Type
Recombinant
Applications
WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the COX IV antibody at -20oC.
Limitations
This COX IV antibody is available for research use only.
Storage Conditions
Store the COX IV antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the COX IV antibody should be determined by the researcher.
Image Legend
Western blot testing of human HepG2 cell lysate with COX IV antibody. Predicted molecular weight ~20 kDa.
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