Ku70 Antibody / XRCC6
The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V (D) J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [RefSeq]
Product Specifications
CAS Number
9000-83-3
Specifications
Western blot: 1:500-1:2000, Immunohistochemistry (FFPE) : 1:50-1:200
UniProt
P12956
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide specific to human Ku70 / XRCC6 was used as the immunogen for the Ku70 antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
AAIG-24
Type
Recombinant
Applications
IHC-P, WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the Ku70 antibody at -20oC.
Limitations
This Ku70 antibody is available for research use only.
Storage Conditions
Store the Ku70 antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the Ku70 antibody should be determined by the researcher.
Location
Nuclear
Image Legend
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
![Ribonuclease 7 (RNASE7) Mouse Monoclonal Antibody [Clone ID: 3C2]](https://cdn.genprice.uk/products/937/68dd189e061270361e8fd5d9/imageurl/am33434pu-n.webp)
Ribonuclease 7 (RNASE7) Mouse Monoclonal Antibody [Clone ID: 3C2]
