Ku70 Antibody / XRCC6
The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V (D) J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [RefSeq]
Product Specifications
CAS Number
9000-83-3
Specifications
Western blot: 1:500-1:2000, Immunohistochemistry (FFPE) : 1:50-1:200
UniProt
P12956
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide specific to human Ku70 / XRCC6 was used as the immunogen for the Ku70 antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
AAIG-24
Type
Recombinant
Applications
IHC-P, WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the Ku70 antibody at -20oC.
Limitations
This Ku70 antibody is available for research use only.
Storage Conditions
Store the Ku70 antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the Ku70 antibody should be determined by the researcher.
Location
Nuclear
Image Legend
Frequently Asked Questions
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