PCNA Antibody
The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. [RefSeq]
Product Specifications
CAS Number
9000-83-3
Specifications
Western blot: 1:3000-1:10000, Immunohistochemistry (FFPE) : 1:50-1:200
UniProt
P12004
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A synthetic peptide specific to human PCNA was used as the immunogen for the PCNA antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
DO-16
Type
Recombinant
Applications
IHC-P, WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the PCNA antibody at -20oC.
Limitations
This PCNA antibody is available for research use only.
Storage Conditions
Store the PCNA antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the PCNA antibody should be determined by the researcher.
Location
Nuclear
Image Legend
Frequently Asked Questions
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