TOP1 Antibody / Topoisomerase I
The TOP1 gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22. [RefSeq]
Product Specifications
CAS Number
9000-83-3
Specifications
Western blot: 1:1000-1:2000
UniProt
P11387
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A synthetic peptide specific to human Topoisomerase I / TOP1 was used as the immunogen for the TOP1 antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
FIG-20
Type
Recombinant
Applications
WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the TOP1 antibody at -20oC.
Limitations
This TOP1 antibody is available for research use only.
Storage Conditions
Store the TOP1 antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the TOP1 antibody should be determined by the researcher.
Image Legend
Western blot testing of human Jurkat cell lysate with TOP1 antibody. Expected molecular weight: 91-100 kDa.
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