PIM1 Antibody
The protein encoded by the PIM1 gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons. [RefSeq]
Product Specifications
CAS Number
9000-83-3
Specifications
Western blot: 1:5000-1:10000, Immunohistochemistry (FFPE) : 1:50-1:200
UniProt
P11309
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A synthetic peptide specific to human PIM1 was used as the immunogen for the PIM1 antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
ECB-16
Type
Recombinant
Applications
IHC-P, WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the PIM1 antibody at -20oC.
Limitations
This PIM1 antibody is available for research use only.
Storage Conditions
Store the PIM1 antibody at -20°C.
Product Datasheet
https://www.nsjbio.com/tds-pdf/pim1-antibody-ecb-16-rq5360
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the PIM1 antibody should be determined by the researcher.
Location
Nuclear, cytoplasmic, cell membrane
Image Legend
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