C-Kit Antibody / KIT / CD117
The KIT gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor) . Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. [RefSeq]
Product Specifications
CAS Number
9000-83-3
Specifications
Western blot: 1:500-1:2000, Immunohistochemistry (FFPE) : 1:50-1:200
UniProt
P10721
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide specific to human c-Kit / KIT was used as the immunogen for the c-Kit antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
CGF-11
Type
Recombinant
Applications
IHC-P, WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the c-Kit antibody at -20oC.
Limitations
This c-Kit antibody is available for research use only.
Storage Conditions
Store the c-Kit antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the c-Kit antibody should be determined by the researcher.
Image Legend
Western blot testing of human fetal lung lysate with c-Kit antibody. Observed molecular weight: ~120/145kDa (precusor/mature) .
Frequently Asked Questions
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