C4A Antibody / Complement C4A
This gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain is cleaved to release C4 anaphylatoxin, an antimicrobial peptide and a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. [RefSeq]
Product Specifications
CAS Number
9000-83-3
Specifications
Western blot: 1:500-1:2000
UniProt
P0C0L4
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide specific to human C4A / Complement C4A was used as the immunogen for the C4A antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
AFHB-3
Type
Recombinant
Applications
WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the C4A antibody at -20oC.
Limitations
This C4A antibody is available for research use only.
Storage Conditions
Store the C4A antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the C4A antibody should be determined by the researcher.
Image Legend
Western blot testing of human HepG2 cell lysate with C4A antibody. Predicted molecular weight: 193-203 kDa (C4A) and 93-98 kDa (C4A alpha chain) .
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
CD57 (Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1, Beta-1,3-glucuronyltransferase 1, Glucuronosyltransferase P, GlcAT-P, UDP-GlcUA:Glycoprotein beta-1,3-glucuronyltransferase, GlcUAT-P, B3GAT1, GLCATP) (FITC)
CD57 (Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1, Beta-1,3-glucuronyltransferase 1, Glucuronosyltransferase P, GlcAT-P, UDP-GlcUA:Glycoprotein beta-1,3-glucuronyltransferase, GlcUAT-P, B3GAT1, GLCATP) (FITC)
CD57 (Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1, Beta-1,3-glucuronyltransferase 1, Glucuronosyltransferase P, GlcAT-P, UDP-GlcUA:Glycoprotein beta-1,3-glucuronyltransferase, GlcUAT-P, B3GAT1, GLCATP) (FITC)
