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Phospho-PDGFRB Antibody (pY740)

The protein encoded by the PDGFRB gene is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer (PDGFB or PDGFD) or a heterodimer (PDGFA and PDGFB) . This gene is essential for normal development of the cardiovascular system and aids in rearrangement of the actin cytoskeleton. [RefSeq]

Product Specifications

CAS Number

9000-83-3

Specifications

Western blot: 1:1000-1:2000

UniProt

P09619

Host

Rabbit

Reactivity

Mouse

Immunogen

A synthetic peptide specific to PDGF Receptor beta (surrounding phosphorylated Y740) was used as the immunogen for the phospho-PDGFRB antibody.

Clonality

Monoclonal

Isotype

IgG

Clone

FDF-16

Type

Recombinant

Applications

WB

Purity

Affinity purified

Format

Purified

Buffer

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA

Reconstitution

Store the phospho-PDGFRB antibody (pY740) at -20oC.

Limitations

This phospho-PDGFRB antibody (pY740) is available for research use only.

Storage Conditions

Store the phospho-PDGFRB antibody (pY740) at -20°C.

Formulation

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA

Applications Notes

Optimal dilution of the phospho-PDGFRB antibody (pY740) should be determined by the researcher.

Image Legend

Western blot testing of lysate from PDGF-treated mouse NIH3T3 cells with phospho-PDGFRB antibody (pY740) . Expected molecular weight: 123-190 kDa depending on level of glycosylation.

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