PDGFRB Antibody
The protein encoded by the PDGFRB gene is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer (PDGFB or PDGFD) or a heterodimer (PDGFA and PDGFB) . This gene is essential for normal development of the cardiovascular system and aids in rearrangement of the actin cytoskeleton. [RefSeq]
Product Specifications
CAS Number
9000-83-3
Specifications
Western blot: 1:500-1:2000, Immunohistochemistry (FFPE) : 1:50-1:200
UniProt
P09619
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide specific to human PDGF Receptor beta / PDGFRB was used as the immunogen for the PDGFRB antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
AGG-16
Type
Recombinant
Applications
IHC-P, WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the PDGFRB antibody at -20oC.
Limitations
This PDGFRB antibody is available for research use only.
Storage Conditions
Store the PDGFRB antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the PDGFRB antibody should be determined by the researcher.
Location
Cell membrane, cytoplasmic (lysosome)
Image Legend
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