CD63 Antibody / LAMP-3
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. [RefSeq]
Product Specifications
CAS Number
9000-83-3
Specifications
Western blot: 1:1000-1:2000, Immunohistochemistry (FFPE) : 1:50-1:200
UniProt
P08962
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide specific to human CD63 was used as the immunogen for the CD63 antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
BGG-3
Type
Recombinant
Applications
IHC-P, WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the CD63 antibody at -20oC.
Limitations
This CD63 antibody is available for research use only.
Storage Conditions
Store the CD63 antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the CD63 antibody should be determined by the researcher.
Image Legend
Western blot testing of human A375 cell lysate with CD63 antibody. Expected molecular weight: 25-60 kDa depending on glycosylation level.
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