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ITGA5 Antibody / Integrin alpha 5

The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [RefSeq]

Product Specifications

CAS Number

9000-83-3

Specifications

Western blot: 1:1000-1:2000

UniProt

P08648

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A synthetic peptide specific to human Integrin alpha 5 / ITGA5 was used as the immunogen for the ITGA5 antibody.

Clonality

Monoclonal

Isotype

IgG

Clone

IDB-9

Type

Recombinant

Applications

WB

Purity

Affinity purified

Format

Purified

Buffer

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA

Reconstitution

Store the ITGA5 antibody at -20oC.

Limitations

This ITGA5 antibody is available for research use only.

Storage Conditions

Store the ITGA5 antibody at -20°C.

Formulation

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA

Applications Notes

Optimal dilution of the ITGA5 antibody should be determined by the researcher.

Image Legend

Western blot testing of mouse heart lysate with ITGA5 antibody. Expected molecular weight: 115-160 kDa depending on glycosylation level. An ~25 kDa band corresponding to the ITGA5 light chain may also be detected.

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