CD41 Antibody / ITGA2B
The ITGA2B gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system, by mediating platelet aggregation. Mutations in this gene are associated with platelet-type bleeding disorders, which are characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia. [RefSeq]
Product Specifications
CAS Number
9000-83-3
Specifications
Western blot: 1:500-1:1000
UniProt
P08514
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide specific to human CD41 / ITGA2B was used as the immunogen for the CD41 antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
AAGH-9
Type
Recombinant
Applications
WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the CD41 antibody at -20oC.
Limitations
This CD41 antibody is available for research use only.
Storage Conditions
Store the CD41 antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the CD41 antibody should be determined by the researcher.
Image Legend
Western blot testing of human fetal liver lysate with CD41 antibody. Expected molecular weight ~120 kDa (alpha chain) and ~23 kDa (beta chain) .
Frequently Asked Questions
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