Neprilysin Antibody / CD10
The protein encoded by this gene is a type II transmembrane glycoprotein and a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL) . The encoded protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. [RefSeq]
Product Specifications
CAS Number
9000-83-3
Specifications
Western blot: 1:1000-1:2000
UniProt
P08473
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide specific to human CD10 / Neprilysin was used as the immunogen for the Neprilysin antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
GEH-13
Type
Recombinant
Applications
WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the Neprilysin antibody at -20oC.
Limitations
This Neprilysin antibody is available for research use only.
Storage Conditions
Store the Neprilysin antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the Neprilysin antibody should be determined by the researcher.
Image Legend
Western blot testing of human Jurkat cell lysate with Neprilysin antibody. Routinely visualized at ~100 kDa.
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